Philip W Kantoff Selected Research

DNA (Deoxyribonucleic Acid)

1/2024	Quantifying Y chromosome loss in primary and metastatic prostate cancer by chromosome painting.
1/2020	Oncogenic Genomic Alterations, Clinical Phenotypes, and Outcomes in Metastatic Castration-Sensitive Prostate Cancer.
7/2019	Novel RB1-Loss Transcriptomic Signature Is Associated with Poor Clinical Outcomes across Cancer Types.
7/2017	Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making.
1/2017	Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing.
8/2016	Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
4/2015	DNA copy number analysis of metastatic urothelial carcinoma with comparison to primary tumors.
8/2014	FGFR3 expression in primary and metastatic urothelial carcinoma of the bladder.
4/2014	Integrative analysis of 1q23.3 copy-number gain in metastatic urothelial carcinoma.
11/2013	Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug.

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Philip W Kantoff Research Topics

Disease

264	Prostatic Neoplasms (Prostate Cancer) 05/2024 - 01/2002
129	Neoplasms (Cancer) 01/2024 - 01/2002
25	Neoplasm Metastasis (Metastasis) 01/2022 - 02/2002
11	Carcinoma (Carcinomatosis) 01/2016 - 02/2002
10	Leukemia 01/2019 - 04/2003
9	Carcinogenesis 11/2015 - 05/2002
8	Disease Progression 01/2018 - 10/2004
7	Adenocarcinoma 12/2022 - 04/2003
5	Pain (Aches) 12/2023 - 05/2008
5	Inflammation (Inflammations) 01/2020 - 11/2012
5	7 Hereditary Prostate Cancer 05/2016 - 05/2009
4	Fatigue 01/2020 - 06/2018
3	Breast Neoplasms (Breast Cancer) 09/2017 - 02/2002
3	Residual Neoplasm 05/2017 - 11/2014
3	Renal Cell Carcinoma (Grawitz Tumor) 11/2015 - 01/2002
2	Circulating Neoplastic Cells 01/2020 - 05/2014
2	Hypertension (High Blood Pressure) 01/2019 - 01/2016

Drug/Important Bio-Agent (IBA)

88	AndrogensIBA 10/2023 - 02/2002
59	Prostate-Specific Antigen (Semenogelase)IBA 01/2022 - 02/2002
42	Hormones (Hormone)IBA 01/2024 - 01/2002
28	Androgen Receptors (Androgen Receptor)IBA 12/2022 - 02/2002
26	Biomarkers (Surrogate Marker)IBA 12/2021 - 10/2003
21	Proteins (Proteins, Gene)FDA Link 05/2024 - 12/2004
20	sipuleucel-T (APC8015)FDA Link 01/2020 - 07/2010
17	DNA (Deoxyribonucleic Acid)IBA 01/2024 - 12/2003
15	Docetaxel (Taxotere)FDA Link 12/2022 - 01/2005
12	Abiraterone AcetateIBA 01/2021 - 09/2012
11	Messenger RNA (mRNA)IBA 10/2023 - 06/2003
11	Testosterone (Sustanon)FDA Link 10/2023 - 07/2003
10	enzalutamideIBA 01/2021 - 05/2015
9	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2006
8	SteroidsIBA 01/2020 - 01/2002
8	AntigensIBA 01/2016 - 04/2006
7	Transcription Factors (Transcription Factor)IBA 12/2022 - 10/2003
6	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2023 - 07/2015
6	PlatinumIBA 01/2020 - 02/2012
6	EnzymesIBA 01/2019 - 01/2002
6	SeleniumIBA 05/2016 - 03/2005
6	thiamine triphosphorate (TTP)IBA 02/2016 - 07/2005
5	abirateroneIBA 06/2018 - 03/2015
5	Leuprolide (Lupron)FDA LinkGeneric 01/2018 - 02/2002
5	Gonadotropin-Releasing Hormone (GnRH)FDA Link 05/2017 - 02/2002
5	Dutasteride (Avodart)FDA Link 05/2017 - 10/2009
5	VaccinesIBA 01/2016 - 03/2010
5	Ketoconazole (Nizoral)FDA LinkGeneric 03/2015 - 09/2006
5	Androgen Antagonists (Antiandrogens)IBA 07/2012 - 07/2003
5	Estrogens (Estrogen)FDA Link 12/2011 - 01/2002
5	VA 061 (VA061)IBA 09/2006 - 07/2003
4	Formaldehyde (Formol)FDA Link 11/2020 - 08/2014
4	ParaffinIBA 11/2020 - 08/2014
4	Immune Checkpoint InhibitorsIBA 04/2019 - 08/2011
4	MicroRNAs (MicroRNA)IBA 01/2019 - 07/2009
4	PROSTVACIBA 01/2019 - 08/2011
4	Carboplatin (JM8)FDA LinkGeneric 09/2017 - 01/2005
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 02/2004
3	antineoplaston A10 (A 10)IBA 12/2023 - 04/2006
3	Lysine (L-Lysine)FDA Link 12/2022 - 05/2016
3	ChromatinIBA 12/2022 - 01/2014
3	NucleotidesIBA 01/2022 - 08/2003
3	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 01/2020
3	Serine Proteases (Serine Protease)IBA 01/2022 - 06/2008
3	LipidsIBA 01/2019 - 04/2015
3	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2019 - 10/2003
3	Prednisone (Sone)FDA LinkGeneric 01/2019 - 07/2017
3	Radium-223IBA 01/2019 - 12/2013
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2018 - 12/2007
3	cabozantinibIBA 06/2018 - 11/2015
3	Bevacizumab (Avastin)FDA Link 01/2016 - 10/2012
3	Everolimus FDA Link 11/2015 - 12/2012
3	AntioxidantsIBA 08/2015 - 03/2005
3	Flutamide (Eulexin)FDA LinkGeneric 03/2015 - 07/2003
3	AutoantigensIBA 11/2012 - 08/2011
3	Gonadal Steroid Hormones (Sex Hormones)IBA 12/2011 - 05/2005
3	Peptides (Polypeptides)IBA 05/2011 - 09/2005
3	LigandsIBA 03/2011 - 10/2003
3	Finasteride (Propecia)FDA LinkGeneric 02/2004 - 07/2003
2	Taxoids (Taxanes)IBA 12/2022 - 06/2006
2	Histone DemethylasesIBA 12/2022 - 01/2018
2	cabazitaxel FDA Link 12/2022 - 01/2018
2	Dasatinib (BMS 354825)FDA Link 01/2022 - 01/2021
2	TensinsIBA 01/2020 - 11/2018
2	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 01/2020 - 01/2019
2	BRCA1 ProteinIBA 01/2020 - 04/2010
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2020 - 11/2018
2	Denosumab FDA Link 01/2019 - 05/2015
2	25-hydroxyvitamin DIBA 01/2019 - 06/2011
2	Vitamin D FDA LinkGeneric 01/2019 - 06/2011
2	CD100 antigenIBA 01/2019 - 11/2012
2	Histones (Histone)IBA 01/2019 - 01/2018
2	hydroxide ionIBA 01/2019 - 06/2011
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 11/2018 - 02/2003

Therapy/Procedure

108	Therapeutics 10/2023 - 02/2002
86	Castration 01/2024 - 07/2003
25	Drug Therapy (Chemotherapy) 01/2020 - 09/2002
22	Radiotherapy 01/2021 - 06/2003
20	Prostatectomy (Retropubic Prostatectomy) 04/2018 - 11/2003
18	Immunotherapy 12/2019 - 03/2010
5	Aftercare (After-Treatment) 01/2020 - 06/2008
5	Brachytherapy 09/2012 - 11/2003
4	Neoadjuvant Therapy 05/2017 - 01/2006